In order to obtain human eye fundus images with high spatial resolution,the liquid crystal (LC) adaptive optics (AO) systems was introduced to the traditional ophthalmoscopes. The AO system based on Shark-Hartmann wavefront sensor (SHWS) and liquid-crystal-on-silicon spatial light modulator(LCOS-SLM) could detect and correct the low and high orders eye′s aberrations,and obtain the human eye fundus images with high spatial resolution. It is a useful tool for early diagnosing the eye diseases and diseases interrelated to the eye. The open-loop and closed-loop mode were both adopted. They could both obtain human eye fundus images with high spatial resolution. The LC-AO system possesses a great potential in human eye fundus imaging with high spatial resolution.