This study selected several types of slag with different titanium content, and subjected them to re-melting and water quenching treatment. Various analytical techniques, such as XRD, DSC, FT-IR and XPS were used to analyze the changes in the amorphous network structures of Al—O, Ti—O and Si—O in slag before and after remelting treatment. The research results show that as the titanium content increases, Al3+ and Ti4+ in the raw slag tend to exist in a highly coordinated form with poor stability, which weakens the resistance of its vitreous structure to thermal changes, manifested by a decrease of glass transition temperature Tg and crystallization temperature Tx. After remelting and rapid cooling, Ti4+ and Al3+ in high-titanium slag tend to exist in a low coordination form with the increase of titanium content. The increase of these network forming bodies leads to an increase in the stability of the vitreous structure, which is manifested by a significant decrease in the activity of the slag in the later stage. This indicates that the performance of slag is not only affected by alkalinity and glass content, but also closely related to the structural changes of the amorphous network.