In order to study the launching tactics for the protection system of vehicle-mounted rocket smoke bomb to realize continuously shielding and protecting its own side target with minimum bomb consumption, when the protection system defends its team from the assault of reconnaissance and striking integrated unmanned aerial vehicle (UAV), the model of smoke bomb defending UAV with its team for numerical simulation is established. The simulation model has considered the influences of horizontal wind and UAV movement on launching parameters such as azimuth, pitching angle and explode time delay, and the wind induced ballistic deviation is corrected, the wind drift area of smokescreen is compensated. The bomb consumption of different launching parameters considering UAV movement is worked out. According to the analysis of simulation results, when defending reconnaissance and striking integrated UAV, the protection system of vehicle-mounted rocket smoke bomb, acting as part of terminal defense force, can usually realize continuously protecting its nearby targets with minimum bomb consumption, through selecting the smallest pitching angle, in the premise of ensuring that smoke bombs are able to be launched to the area that should be covered by smoke.