Acta Physica Sinica, Volume. 68, Issue 17, 178702-1(2019)

Magnetocardiogram forward problem based on personalized three-dimensional heart-torso model

Wei-Wei Xu1,2, Ming-Zhu Bai1,2, Qiang Lin1,2, and Zheng-Hui Hu1,2、*
Author Affiliations
  • 1College of Science, Zhejiang University of Technology, Hangzhou 310023, China
  • 2Collaborative Innovation Center for Bio-Med Physics Information Technology, Zhejiang University of Technology, Hangzhou 310023, China
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    In order to simulate the distribution of magnetic field generated by cardiac electrophysiological activities, a three-dimensional (3D) computing framework of magnetocardiogram forward problem based on a finite element method (FEM) is proposed. First, the 3D heart-torso geometry model is established from the 3D reconstruction of magnetic resonance images. Then the modified FitzHugh-Nagumo (FHN) equation combined with 3D cardiac geometry is used to investigate the propagation of transmembrane potential (TMP). In the end, quasi-static Maxwell equations and 3D torso model are used to explore the propagation of the bioelectromagnetic field produced by TMP. In our calculation, the Galerkin finite element method is used. The results show that the FEM-model can simulate extracorporeal magnetic field. Further, numerical solutions of simplified models with the one-dimensional FHN equation and the straight wire are respectively consistent with the analytical solutions, which verifies the feasibility of the computing framework. In summary, this framework successfully simulates the cardiac TMP and extracorporeal magnetic field, which may conduce to the study of magnetocardiogram inverse problem.

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    Wei-Wei Xu, Ming-Zhu Bai, Qiang Lin, Zheng-Hui Hu. Magnetocardiogram forward problem based on personalized three-dimensional heart-torso model[J]. Acta Physica Sinica, 2019, 68(17): 178702-1

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    Paper Information

    Received: Mar. 18, 2019

    Accepted: --

    Published Online: Sep. 16, 2020

    The Author Email:

    DOI:10.7498/aps.68.20190387

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