Target restoration in transmission scattering imaging has attracted much attention in the fields of biomedicine, remote sensing, and security. In this paper, we construct a target restoration model based on the digital holographic scattering imaging theory. The key factors affecting the target restoration in the model are systematically simulated and analyzed, such as the center wavelength of the laser source, target size, observation distance, scattering medium characteristics, and detector resolution. The results show that the laser source with a central wavelength of 635.5 nm, a detector with an observation distance of 50 cm and a spatial resolution of 512 pixel×512 pixel, a diffuser with a root mean square roughness of 333 μm, and the diffuser with Gaussian random distribution model under close root mean square roughness conditions, are more conducive to the target restoration. This research provides a basis for the rapid and accurate construction of an image restoration system applied in transmission scattering imaging.