Aluminum-lithium alloy is considered to be one of the promising light-weight materials for aerospace applications. In the experiment, T-joint of 2060-T8/2099-T83 aluminum-lithium alloy with thickness of 2 mm is welded by using two high brightness solid state lasers from the two sides of the stringer aimed to integral aircraft fuselage panels. The weld porosity, cracking and joint mechanical properties are investigated. The results show that macro hydrogen pores can be avoided only when the surface layers are removed at least 0.15 mm thick, while the hot cracking can be completely eliminated with filler wire of AlSi12 and an appropriate bevel design. The hoop tensile strength of laser-welded T-joints is among 385~415 MPa, 82.5 % of that of the 2060-T8 skin sheet. The bond is the weakest region of the joint.