Humans observe the world through their eyes and optical instruments, but scattering seriously disrupts light propagation, making focusing and imaging extremely difficult through the scattering medium. By modulating the phase of the input light through feedback optimization, the wavefront distortion caused by scattering can be corrected, allowing light to focus on a specific target in the output light field. Therefore, we propose a memetic algorithm-based method for focusing through a scattering medium. The method combines global search and local search, abstracting focusing through scattering medium into the process of cultural evolution. The simulation and experimental results show that, when compared to focusing methods based on genetic algorithm and particle swarm optimization algorithm, the method has obvious advantages in focusing effect and time consumption, and has good application potential in the field of light field control.