A new model was built for light propagation in two-dimensional anisotropic random medium, and the dielectric constant distribution was precisely described. The optical property of light waves in two-dimensional random media with uniaxial scattering particles was investigated by simultaneously solving Maxwell’s equations and rate equations of electronic population. Results show that ordered scatterers in anisotropic material can also form localization of light-waves if the index of refraction of the uniaxial scatterers distribute randomly in two-dimensional media. The randomness of rotation angle of the optic axis determines the index of refraction of each scattering particle and reinforces the random lasing in random media.