Journal of Innovative Optical Health Sciences, Volume. 11, Issue 1, 1750017(2018)

Comparative evaluations of the Monte Carlo-based light propagation simulation packages for optical imaging

Lin Wang1, Shenghan Ren2, and Xueli Chen2、*
Author Affiliations
  • 1School of Information Sciences and Technology, Northwest University, Xi'an Shaanxi 710127, P. R. China
  • 2Engineering Research Center of Molecular and Neuro Imaging of Ministry of Education, School of Life Science and Technology, Xidian University, Xi'an Shaanxi 710126, P. R. China
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    Monte Carlo simulation of light propagation in turbid medium has been studied for years. A number of software packages have been developed to handle with such issue. However, it is hard to compare these simulation packages, especially for tissues with complex heterogeneous structures. Here, we first designed a group of mesh datasets generated by Iso2Mesh software, and used them to cross-validate the accuracy and to evaluate the performance of four Monte Carlobased simulation packages, including Monte Carlo model of steady-state light transport in multilayered tissues (MCML), tetrahedron-based inhomogeneous Monte Carlo optical simulator (TIMOS), Molecular Optical Simulation Environment (MOSE), and Mesh-based Monte Carlo (MMC). The performance of each package was evaluated based on the designed mesh datasets. The merits and demerits of each package were also discussed. Comparative results showed that the TIMOS package provided the best performance, which proved to be a reliable, e±cient, and stable MC simulation package for users.

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    Lin Wang, Shenghan Ren, Xueli Chen. Comparative evaluations of the Monte Carlo-based light propagation simulation packages for optical imaging[J]. Journal of Innovative Optical Health Sciences, 2018, 11(1): 1750017

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    Paper Information

    Received: Jan. 4, 2017

    Accepted: May. 3, 2017

    Published Online: Sep. 17, 2018

    The Author Email: Chen Xueli (xlchen@xidian.edu.cn)

    DOI:10.1142/s1793545817500171

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