The effects of the doping material, concentration and fiber structure on the frequency shift and Brillouin scattering efficiency of depolarized guided acoustic wave Brillouin scattering in single mode fiber and photonic crystal fiber are investigated by the all-vector finite element method. The results show that the Brillouin frequency shift of the two kinds of fibers decrease and scattering efficiency of the single mode fiber increase with the increase of doped F concentrationin the cladding and doped GeO2concentrationin the core. The Brillouin frequency shift decreases with the increasing number of air holes rings at the given doped F concentration in photonic crystal fiber. The Brillouin frequency shift of TR2,3 mode increases, but that of TR2,7 modedecreases with the increasing number of air holes rings at a given doped GeO2concentration in fiber core.