Different entangled states are usually required for realization of different quantum information processes. A special five-particle entangled state was proved to be used in several quantum information processes such as quantum teleportation, quantum state sharing and quantum dense coding. Based on cavity quantum electrodynamics, a preparation scheme of the special five-particle entangled state is proposed. The atoms and cavity field are chosen in a certain initial state. Multiple atoms interact with each other in cavity field and the interaction time is selected. By means of the classical unitary transformation, the five atoms are prepared in a special entangled state. There is no energy exchange between the atoms and cavity field during the whole preparation process, and no quantum measurement is needed, which makes the scheme more easily implemented in experiment.