Binary regression analysis algorithm is proposed and adopted to realize the temperature compensation model of fiber Bragg grating (FBG) strain sensor through analyzing the basic operation principle of the sensor and the issues of FBG strain and temperature cross sensitivity. Computer program and experiment results show that the temperature sensitivity coefficient is lower from 2.74×10-2/℃ to 9.16×10-5/℃ after data fusion processing. And the temperature cross sensitivity is obviously improved to meet the actual measurement requirements of strain measurement in high-temperature pressure conduit.